Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24381880 | 1.00 | THRB (0.60) | THRBLMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5470045 | 0.86 | TAS1R3 (0.66) | THRBMAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL29620026 | 0.84 | RAB9A (0.56) | LMNAMAPTALDH1A1KDM4ETAS1R3 | |
| SCHEMBL24381897 | 0.84 | RAB9A (0.56) | LMNAMAPTALDH1A1KDM4ETAS1R3 | |
| SCHEMBL14924439 | 0.84 | PANK3 (0.57) | LMNAMAPTSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL17450444 | 0.83 | MAPT (0.50) | THRBMAPTSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL29620017 | 0.83 | MAPT (0.71) | LMNAMAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL24381815 | 0.83 | MAPT (0.71) | LMNAMAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL20660701 | 0.83 | MAPT (0.71) | THRBLMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24382014 | 0.82 | KDM4E (0.47) | THRBMAPTSMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240741-A1 | IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND THEIR USE AS ATM KINASE INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022096361-A1 | IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND THEIR USE AS ATM KINASE INHIBITORS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2022-05-12 | — | — | WO | disclosed |