Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24333441 | 1.00 | TRPV3 (0.33) | TRPV3MAP3K14TNKSPARP1TNKS2 | |
| SCHEMBL13058585 | 0.75 | — | — | |
| SCHEMBL26684995 | 0.73 | CCNA2 (0.34) | — | |
| SCHEMBL23967093 | 0.73 | — | — | |
| SCHEMBL22528538 | 0.73 | — | — | |
| SCHEMBL31631820 | 0.73 | — | — | |
| SCHEMBL16026134 | 0.72 | — | — | |
| SCHEMBL16077137 | 0.72 | — | — | |
| SCHEMBL17742617 | 0.72 | — | — | |
| SCHEMBL15065650 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082174-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | NUVATION BIO OPERATING COMPANY INC. (US) | 2022-04-21 | — | — | WO | disclosed |