Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23361739 | 1.00 | MAPT (0.49) | MAPTGAAATML3MBTL1ALDH1A1 | |
| SCHEMBL27157705 | 0.83 | GABRB3 (0.46) | — | |
| SCHEMBL27157703 | 0.76 | CDK4 (0.38) | L3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL769495 | 0.73 | CYP1A2 (0.61) | ALDH1A1SMN1; SMN2RAB9AKMT2ALMNA | |
| SCHEMBL30681840 | 0.73 | MAPT (0.39) | MAPTGAAL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27157905 | 0.73 | MAPT (0.39) | MAPTGAAL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27157671 | 0.72 | OPRM1 (0.41) | L3MBTL1ALDH1A1LMNACNR1CNR2 | |
| SCHEMBL27158265 | 0.72 | CASR (0.39) | MAPTATML3MBTL1RAB9A | |
| SCHEMBL27157689 | 0.70 | PTGS2 (0.46) | MAPTGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL14996685 | 0.69 | GAA (0.53) | MAPTGAAATML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555581-B | Fluorine-containing pyrazole compound and preparation method thereof | 优迈特株式会社 | 2024-05-24 | — | — | CN | disclosed |
| EP-4059927-A1 | FLUORINE-CONTAINING PYRAZOLE COMPOUND AND METHOD FOR PRODUCING SAME | Unimatec Co., Ltd. (JP) | 2022-09-21 | — | — | EP | disclosed |
| CN-114555581-A | Fluorine-containing pyrazole compound and preparation method thereof | 优迈特株式会社 | 2022-05-27 | — | — | CN | disclosed |