Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23407614 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL29620817 | 0.92 | KLK7 (0.47) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL23407653 | 0.92 | KLK7 (0.47) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL22394740 | 0.90 | GAA (0.46) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL29620764 | 0.90 | GAA (0.46) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL29620846 | 0.90 | KLK7 (0.46) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL23407549 | 0.90 | KLK7 (0.46) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL23407651 | 0.88 | TUBB4A (0.44) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL29620843 | 0.88 | TUBB4A (0.44) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL23407709 | 0.87 | KLK7 (0.43) | ALDH1A1KDM4ERAB9AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220372027-A1 | ANTIBACTERIAL COMPOUNDS | DISCUVA LTD. (GB) | 2022-11-24 | — | — | US | disclosed |
| US-11345694-B2 | Antibacterial compounds | DISCUVA LTD. (GB) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345694-B2 | Antibacterial compounds | CFTR, MRPL21, NQO1 | ALDH1A1 1908/4885KDM4E 4533/4885RAB9A 802/4885 |
| US-20220372027-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, NRDC, PGLS | ALDH1A1 3982/4885KDM4E 3363/4885RAB9A 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.