Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388303 | 0.75 | APLNR (0.58) | APLNRALDH1A1ABCB11NR3C1CYP1A2 | |
| SCHEMBL23577138 | 0.73 | APLNR (0.61) | APLNRALDH1A1ABCB11NR3C1CYP1A2 | |
| SCHEMBL21597747 | 0.73 | APLNR (0.56) | APLNRALDH1A1ABCB11NR3C1CYP1A2 | |
| SCHEMBL190351 | 0.73 | APLNR (0.56) | APLNRALDH1A1ABCB11NR3C1CYP1A2 | |
| SCHEMBL27532697 | 0.73 | CYP11B1 (0.36) | APLNRCYP11B1PLCG1LRRK2ELANE | |
| SCHEMBL29164469 | 0.71 | APLNR (0.33) | APLNR | |
| SCHEMBL14257313 | 0.70 | APLNR (0.53) | APLNRALDH1A1ABCB11NR3C1CYP1A2 | |
| SCHEMBL12456472 | 0.70 | APLNR (0.42) | APLNRALDH1A1ABCB11NR3C1CYP1A2 | |
| SCHEMBL2350798 | 0.70 | ALDH1A1 (0.53) | APLNRALDH1A1ABCB11NR3C1CYP1A2 | |
| SCHEMBL2828117 | 0.69 | APLNR (1.00) | APLNRALDH1A1ABCB11NR3C1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |