Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 17/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22926103 | 1.00 | CHEK1 (0.38) | CHEK1SCN10ADGAT1KIF11 | |
| SCHEMBL22925622 | 0.88 | DGAT1 (0.41) | CHEK1DGAT1 | |
| SCHEMBL22926108 | 0.79 | CASP3 (0.43) | CHEK1 | |
| SCHEMBL22925945 | 0.77 | LRRK2 (0.40) | CHEK1SCN10ADGAT1KIF11 | |
| SCHEMBL22925768 | 0.77 | MAPK1 (0.39) | KIF11 | |
| SCHEMBL22925818 | 0.77 | MAPK1 (0.39) | KIF11 | |
| SCHEMBL29696292 | 0.77 | MAPK1 (0.39) | KIF11 | |
| SCHEMBL24636885 | 0.76 | NPSR1 (0.47) | CHEK1 | |
| SCHEMBL22925932 | 0.76 | CHEK1 (0.39) | CHEK1SCN10AKIF11 | |
| SCHEMBL29621039 | 0.76 | NPSR1 (0.47) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |