Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4214379 | 0.83 | LTA4H (0.58) | ABCB1MAPTALDH1A1LMNASGMS2 | |
| SCHEMBL22324256 | 0.81 | NPC1 (0.47) | NPC1RAB9AABCB1MAPTHTT | |
| SCHEMBL12301192 | 0.79 | NPC1 (0.70) | NPC1RAB9AABCB1HTTSMN1; SMN2 | |
| SCHEMBL16740400 | 0.79 | CSF1R (0.47) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL3179011 | 0.78 | PLCG1 (0.47) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL7237455 | 0.78 | NPC1 (0.68) | NPC1RAB9AABCB1MAPTALDH1A1 | |
| SCHEMBL897966 | 0.78 | NPC1 (0.68) | NPC1RAB9AABCB1HTTSMN1; SMN2 | |
| SCHEMBL9125665 | 0.78 | NPC1 (1.00) | NPC1RAB9AABCB1MAPTGAA | |
| SCHEMBL22925751 | 0.77 | MAOB (0.44) | NPC1RAB9AMAPTSMN1; SMN2TSHR | |
| SCHEMBL20447822 | 0.77 | NPC1 (0.47) | NPC1RAB9AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |