Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925885 | 1.00 | GSK3B (0.49) | GSK3BCHEK1QPCTACHECA12 | |
| SCHEMBL22925798 | 0.85 | GSK3B (0.43) | GSK3BCHEK1ACHEHDAC1DGAT1 | |
| SCHEMBL22925918 | 0.83 | VCP (0.44) | GSK3BCHEK1KCNQ3KCNQ2FLT1 | |
| SCHEMBL24636885 | 0.82 | NPSR1 (0.47) | GSK3BCHEK1FLT1KDR | |
| SCHEMBL29621039 | 0.82 | NPSR1 (0.47) | GSK3BCHEK1FLT1KDR | |
| SCHEMBL22925955 | 0.79 | CASP3 (0.42) | CHEK1HDAC1KCNQ3KCNQ2P2RX3 | |
| SCHEMBL31013352 | 0.76 | GSK3B (0.37) | GSK3BQPCTACHECA12CA1 | |
| SCHEMBL28733614 | 0.76 | GSK3B (0.37) | GSK3BQPCTACHECA12CA1 | |
| SCHEMBL22925558 | 0.76 | GSK3B (0.37) | GSK3BQPCTACHECA12CA1 | |
| Hydrochloric Acid SCHEMBL29696318 | 0.75 | GSK3B (0.37) | GSK3BQPCTACHECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |