Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.35 |
| ▸ | TUBB | P07437 | 7/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925824 | 0.86 | TUBB4A (0.44) | CASP3CHEK1TUBB4ATUBBTUBA3C | |
| SCHEMBL22925809 | 0.84 | CHEK1 (0.42) | CASP3CHEK1GRM5KCNH2HDAC4 | |
| SCHEMBL29620949 | 0.83 | TUBB4A (0.38) | CHEK1GRM5TUBB4ATUBBTUBA3C | |
| SCHEMBL22926108 | 0.83 | CASP3 (0.43) | CASP3CHEK1GRM5HDAC4HDAC1 | |
| SCHEMBL28939446 | 0.83 | TUBB4A (0.38) | CHEK1GRM5TUBB4ATUBBTUBA3C | |
| SCHEMBL29620965 | 0.79 | GSK3B (0.49) | CHEK1P2RX3KCNQ3KCNQ2HDAC1 | |
| SCHEMBL22925918 | 0.79 | VCP (0.44) | CHEK1P2RX3KCNQ3KCNQ2 | |
| SCHEMBL22925885 | 0.79 | GSK3B (0.49) | CHEK1P2RX3KCNQ3KCNQ2HDAC1 | |
| SCHEMBL22925723 | 0.76 | CASP3 (0.41) | CASP3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28733724 | 0.76 | CASP3 (0.41) | CASP3TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| US-20220274970-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-09-01 | — | — | US | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274970-A1 | INHIBITOR COMPOUNDS | SERPINB1, MMP1, SSB | CASP3 1714/4885CHEK1 1509/4885GRM5 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.