Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17193258 | 1.00 | NOTUM (0.58) | NOTUMLTA4HROCK2MEN1KMT2A | |
| SCHEMBL22925607 | 0.77 | ROCK2 (0.43) | NOTUMLTA4HROCK2MEN1KMT2A | |
| SCHEMBL6612464 | 0.77 | GAA (0.58) | NOTUMLTA4HROCK2MEN1KMT2A | |
| SCHEMBL9284896 | 0.77 | LMNA (0.58) | NOTUMROCK2MEN1KMT2APTK2 | |
| SCHEMBL3388292 | 0.77 | MAP4K4 (0.47) | NOTUMLTA4HROCK2MEN1KMT2A | |
| SCHEMBL29621110 | 0.77 | GAA (0.58) | NOTUMLTA4HROCK2MEN1KMT2A | |
| SCHEMBL30753615 | 0.77 | MAP4K4 (0.47) | NOTUMLTA4HROCK2MEN1KMT2A | |
| SCHEMBL472353 | 0.74 | NOTUM (1.00) | NOTUMLTA4HMEN1KMT2APTK2 | |
| SCHEMBL197456 | 0.73 | CCR1 (0.46) | PTK2LMNACASP3CNR2 | |
| SCHEMBL31504098 | 0.73 | CCR1 (0.46) | PTK2LMNACASP3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |