Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 7/20 | 0.40 |
| ▸ | FLT1 | P17948 | 5/20 | 0.40 |
| ▸ | FLT4 | P35916 | 5/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.36 |
| ▸ | VCP | P55072 | 2/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620939 | 0.89 | ALOX5 (0.36) | ALOX5KDRFLT1FLT4TRPV1 | |
| SCHEMBL29620992 | 0.87 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL28733644 | 0.76 | ALOX5 (0.46) | ALOX5KDRFLT1FLT4TRPV1 | |
| SCHEMBL22925708 | 0.76 | ALOX5 (0.46) | ALOX5KDRFLT1FLT4TRPV1 | |
| SCHEMBL29620933 | 0.76 | VCP (0.50) | KDRFLT1FLT4TRPV1VCP | |
| SCHEMBL29621015 | 0.75 | P2RY1 (0.37) | ALOX5KDRFLT1FLT4TRPV1 | |
| SCHEMBL29620906 | 0.72 | DGAT1 (0.43) | KDRFLT1FLT4TRPV1P2RY1 | |
| SCHEMBL29620911 | 0.70 | VCP (0.51) | ALOX5KDRFLT1FLT4TRPV1 | |
| SCHEMBL22925745 | 0.67 | TRPV1 (0.48) | ALOX5KDRFLT1FLT4TRPV1 | |
| SCHEMBL22925592 | 0.67 | TRPV1 (0.47) | ALOX5KDRFLT1FLT4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |