Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 12/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 3/20 | 0.35 |
| ▸ | FLT4 | P35916 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925545 | 1.00 | DGAT1 (0.38) | DGAT1CHEK1JAK2JAK1FLT1 | |
| SCHEMBL29620981 | 0.86 | FLT1 (0.44) | DGAT1CHEK1FLT1FLT4KDR | |
| SCHEMBL22925978 | 0.86 | FLT1 (0.44) | DGAT1CHEK1FLT1FLT4KDR | |
| SCHEMBL22925742 | 0.82 | CHEK1 (0.40) | CHEK1FLT1FLT4KDRIMPDH2 | |
| SCHEMBL29620891 | 0.82 | CHEK1 (0.40) | CHEK1FLT1FLT4KDRIMPDH2 | |
| SCHEMBL22925918 | 0.81 | VCP (0.44) | CHEK1FLT1FLT4KDRIMPDH2 | |
| SCHEMBL22925932 | 0.79 | CHEK1 (0.39) | CHEK1FLT1FLT4KDRIMPDH2 | |
| SCHEMBL29620907 | 0.78 | MEN1 (0.40) | CHEK1FLT1FLT4KDRIMPDH2 | |
| SCHEMBL28733613 | 0.78 | MEN1 (0.40) | CHEK1FLT1FLT4KDRIMPDH2 | |
| SCHEMBL22925546 | 0.77 | DGAT1 (0.38) | DGAT1FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |