Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 8/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | FLT1 | P17948 | 2/20 | 0.35 |
| ▸ | FLT4 | P35916 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28733613 | 1.00 | MEN1 (0.40) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL29620982 | 0.88 | IMPDH2 (0.44) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL28733810 | 0.88 | IMPDH2 (0.44) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL22925932 | 0.85 | CHEK1 (0.39) | IMPDH2CHEK1KDRFLT1FLT4 | |
| SCHEMBL22925742 | 0.85 | CHEK1 (0.40) | IMPDH2CHEK1KDRFLT1FLT4 | |
| SCHEMBL29620891 | 0.85 | CHEK1 (0.40) | IMPDH2CHEK1KDRFLT1FLT4 | |
| SCHEMBL22925918 | 0.81 | VCP (0.44) | IMPDH2CHEK1KDRFLT1FLT4 | |
| SCHEMBL28939446 | 0.81 | TUBB4A (0.38) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL29620949 | 0.81 | TUBB4A (0.38) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL24636931 | 0.80 | CHEK1 (0.38) | IMPDH2CHEK1KDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |