Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28803460 | 1.00 | HCAR2 (0.49) | HCAR2CYP2C19HIF1AKMT2AMAPT | |
| SCHEMBL2962178 | 1.00 | HCAR2 (0.49) | HCAR2CYP2C19HIF1AKMT2AMAPT | |
| SCHEMBL2962175 | 0.94 | CYP2C19 (0.48) | HCAR2CYP2C19HIF1AKMT2AMAPT | |
| SCHEMBL7086342 | 0.87 | HCAR2 (0.47) | HCAR2CYP2C19HIF1AKMT2AMAPT | |
| SCHEMBL7086340 | 0.87 | HCAR2 (0.47) | HCAR2CYP2C19HIF1AKMT2AMAPT | |
| SCHEMBL7087313 | 0.87 | HCAR2 (0.47) | HCAR2CYP2C19HIF1AKMT2AMAPT | |
| SCHEMBL9465358 | 0.81 | HCAR2 (0.45) | HCAR2CYP2C19HIF1AKMT2AMAPT | |
| SCHEMBL7083020 | 0.80 | HCAR2 (0.46) | HCAR2CYP2C19HIF1AMAPTLMNA | |
| SCHEMBL30760595 | 0.80 | HCAR2 (0.46) | HCAR2CYP2C19HIF1AMAPTLMNA | |
| SCHEMBL30139633 | 0.80 | HCAR2 (0.46) | HCAR2CYP2C19HIF1AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763263-B2 | Skin external agents and drugs | KAO CORPORATION (JP) | 2010-07-27 | — | — | US | disclosed |
| EP-1249237-B1 | Topical cosmetic and pharmaceutical composition comprising specific alkoxylated diester of fumaric acid | KAO CORP (JP) | 2007-07-18 | — | — | EP | disclosed |
| US-20060177408-A1 | Skin external agents and drugs | KANEBO COSTMETICS INC. | 2006-08-10 | — | — | US | disclosed |
| US-7037489-B2 | Skin external agents and drugs | KANEBO COSMETICS, INC. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20030185786-A1 | Skin external agents and drugs | KAO CORPORATION (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1249237-A1 | SKIN EXTERNAL AGENTS AND DRUGS | Kanebo Limited (JP) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060177408-A1 | Skin external agents and drugs | CUTA, F12, NFE2 | HCAR2 452/4885CYP2C19 1009/4885HIF1A 597/4885 |
| US-20030185786-A1 | Skin external agents and drugs | AREG, RARG, FRG1 | HCAR2 191/4885CYP2C19 2625/4885HIF1A 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.