Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 13/20 | 0.35 |
| ▸ | AKT1 | P31749 | 11/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24377348 | 1.00 | RPS6KB1 (0.35) | RPS6KB1AKT1OPRK1MBOAT4AVPR1A | |
| SCHEMBL26629817 | 0.83 | OPRK1 (0.34) | RPS6KB1AKT1OPRK1HRH4 | |
| SCHEMBL26749958 | 0.79 | RPS6KB1 (0.41) | RPS6KB1AKT1AKT2AKT3 | |
| SCHEMBL26744216 | 0.78 | HTR6 (0.39) | RPS6KB1AKT1OPRK1HRH4 | |
| SCHEMBL26749781 | 0.78 | RPS6KB1 (0.40) | RPS6KB1AKT1AVPR1AHRH4 | |
| SCHEMBL29622069 | 0.78 | LRRK2 (0.34) | RPS6KB1AKT1OPRK1MBOAT4HRH4 | |
| SCHEMBL24377352 | 0.78 | LRRK2 (0.34) | RPS6KB1AKT1OPRK1MBOAT4HRH4 | |
| SCHEMBL26749847 | 0.77 | KDM1A (0.43) | RPS6KB1AKT1AVPR1AHRH4 | |
| SCHEMBL24377345 | 0.76 | QPCT (0.52) | RPS6KB1AKT1AKT2AKT3 | |
| SCHEMBL26741733 | 0.76 | SLC9A1 (0.39) | RPS6KB1AKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205173-A1 | SUBSTITUTED PIPERIDINES AND SUBSTITUTED TETRAHYDROPYRIDINES AS IMMUNE-MODULATING COMPOUNDS | BLACKSMITH MEDICINES, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2022086920-A1 | GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE (QPCTL) PROTEIN INHIBITORS AND USES THEREOF | BLACKSMITH MEDICINES, INC. (US) | 2022-04-28 | — | — | WO | disclosed |