SCHEMBL2962277

SCHEMBL2962277

C1=Cc2cccc(Sc3cccc4c3CC=C4)c2C1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.33
HTR2A P28223 1/20 0.33
SLC6A4 P31645 1/20 0.33
HRH1 P35367 1/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
HTR2B P41595 1/20 0.33
HTR3A P46098 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL276578 0.77 SLC6A2 (0.35) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL8044713 0.76 SLC6A2 (0.34) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL4854314 0.71 SLC6A2 (0.37) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL276579 0.71 BCL2L1 (0.39) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL3784850 0.71 CYP1A2 (0.35) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL11662214 0.71 CYP3A4 (0.35) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL8765141 0.71 SLC6A2 (0.34) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL2974474 0.71 TRPA1 (0.36) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL31285053 0.71 TRPA1 (0.36) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL2859416 0.71 MEN1 (0.41) SLC6A2HTR2ASLC6A4HRH1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 SLC6A2 4215/4885HTR2A 2923/4885SLC6A4 2785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.