SCHEMBL8765141

SCHEMBL8765141

Ic1cccc2c1CC=C2

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.34
HTR2A P28223 1/20 0.34
SLC6A4 P31645 1/20 0.34
HRH1 P35367 1/20 0.34
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34
HTR2B P41595 1/20 0.34
HTR3A P46098 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12320946 0.78
SCHEMBL276578 0.74 SLC6A2 (0.35) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL4854314 0.73 SLC6A2 (0.37) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL11662214 0.73 CYP3A4 (0.35) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL31285053 0.73 TRPA1 (0.36) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL2974474 0.73 TRPA1 (0.36) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL3784850 0.73 CYP1A2 (0.35) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL8044713 0.73 SLC6A2 (0.34) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL276579 0.73 BCL2L1 (0.39) SLC6A2HTR2ASLC6A4HRH1OPRD1
SCHEMBL693026 0.71 PRCP (0.34) SLC6A2HTR2ASLC6A4HRH1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10954178-B1 Synthesis of haloindenes THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2021-03-23 US claimed
US-10954178-B1 Synthesis of haloindenes THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2021-03-23 US disclosed
US-10954178-B1 Synthesis of haloindenes THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2021-03-23 US disclosed
EP-0505972-B1 Process for producing styrenic copolymer IDEMITSU KOSAN CO (JP) 1997-06-11 EP disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed