Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23065257 | 1.00 | DRD2 (0.39) | DRD2TBXA2RKCNH2HRH3 | |
| SCHEMBL29623150 | 0.88 | ACP1 (0.40) | — | |
| SCHEMBL24089897 | 0.88 | ACP1 (0.40) | — | |
| SCHEMBL23064459 | 0.88 | LMNA (0.39) | — | |
| SCHEMBL23065248 | 0.86 | ACP1 (0.39) | — | |
| SCHEMBL29623129 | 0.86 | ACP1 (0.39) | — | |
| SCHEMBL23065073 | 0.85 | ACP1 (0.48) | — | |
| SCHEMBL29623066 | 0.84 | NPC1 (0.40) | — | |
| SCHEMBL23045335 | 0.84 | NPC1 (0.40) | — | |
| SCHEMBL23065072 | 0.84 | ACP1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | claimed |
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | disclosed |