Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 3/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | CCKBR | P32239 | 1/20 | 0.55 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23175238 | 1.00 | MAPT (0.61) | MAPTLMNAPKMHRH3ALDH1A1 | |
| SCHEMBL28373402 | 0.90 | KCNJ5 (0.62) | MAPTLMNAPKMHRH3ALDH1A1 | |
| SCHEMBL11189753 | 0.88 | HRH3 (0.67) | MAPTLMNAPKMHRH3ALDH1A1 | |
| SCHEMBL23175240 | 0.87 | GPR84 (0.54) | MAPTLMNAPKMHSD17B10ANO1 | |
| SCHEMBL31218207 | 0.85 | HRH3 (0.67) | MAPTLMNAHRH3ALDH1A1MEN1 | |
| SCHEMBL7807900 | 0.85 | HRH3 (0.67) | MAPTLMNAHRH3ALDH1A1MEN1 | |
| SCHEMBL28373040 | 0.84 | MAPT (0.65) | MAPTLMNAPKMHRH3ALDH1A1 | |
| SCHEMBL28373392 | 0.83 | MAPT (0.59) | MAPTLMNAPKMHRH3ALDH1A1 | |
| SCHEMBL27333111 | 0.81 | HRH3 (0.67) | MAPTLMNAHRH3ALDH1A1MEN1 | |
| SCHEMBL28167956 | 0.81 | KMT2A (0.76) | MAPTLMNAHRH3ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555583-B | Compounds and their use in the treatment of autoimmune diseases | 帕连齐玛生物技术株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-114555583-A | Novel compounds and their use in the treatment of autoimmune diseases | 帕连齐玛生物技术株式会社 | 2022-05-27 | — | — | CN | disclosed |