Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.62 |
| ▸ | CDC25A | P30304 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | CMA1 | P23946 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341492 | 1.00 | GPR84 (0.62) | GPR84CDC25AKDM4ECMA1MEN1 | |
| SCHEMBL6980980 | 0.86 | KDM4E (0.51) | GPR84CDC25AKDM4ECMA1MEN1 | |
| SCHEMBL8260034 | 0.86 | GPR84 (0.62) | GPR84KDM4EMEN1KMT2APTPN5 | |
| SCHEMBL23175314 | 0.85 | GPR84 (0.61) | GPR84KDM4EMEN1KMT2APTPN5 | |
| SCHEMBL29623198 | 0.85 | GPR84 (0.61) | GPR84KDM4EMEN1KMT2APTPN5 | |
| SCHEMBL30958421 | 0.85 | ICMT (0.62) | GPR84KDM4EMEN1KMT2APTPN5 | |
| SCHEMBL588980 | 0.85 | ICMT (0.62) | GPR84KDM4EMEN1KMT2APTPN5 | |
| Hydrochloric Acid SCHEMBL3155846 | 0.83 | ICMT (0.60) | GPR84KDM4EMEN1KMT2APTPN5 | |
| SCHEMBL1326755 | 0.83 | CMA1 (0.63) | GPR84KDM4ECMA1MEN1KMT2A | |
| SCHEMBL13062120 | 0.83 | KDM4E (0.60) | GPR84KDM4EMEN1KMT2APTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025122501-A1 | BENZOTHIOPHENE-3-YL- AND BENZOSELENOPHENE-3-YL (BICLYCLIC HETEROARYL) MALEMIDES AS GSK-3 INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2025-06-12 | — | — | WO | disclosed |
| CN-114555583-B | Compounds and their use in the treatment of autoimmune diseases | 帕连齐玛生物技术株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-117320715-A | Compounds for the treatment of hyperproliferative diseases | 瓦尔希伯伦私人肿瘤研究基金会 | 2023-12-29 | — | — | CN | disclosed |
| CN-114555583-A | Novel compounds and their use in the treatment of autoimmune diseases | 帕连齐玛生物技术株式会社 | 2022-05-27 | — | — | CN | disclosed |