Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341492 | 0.86 | GPR84 (0.62) | KDM4ECDC25AGPR84CMA1MEN1 | |
| SCHEMBL29623334 | 0.86 | GPR84 (0.62) | KDM4ECDC25AGPR84CMA1MEN1 | |
| SCHEMBL22768845 | 0.79 | GPR84 (0.61) | KDM4EGPR84CMA1MEN1KMT2A | |
| SCHEMBL8260034 | 0.74 | GPR84 (0.62) | KDM4EGPR84MEN1KMT2APTPN5 | |
| SCHEMBL23175314 | 0.73 | GPR84 (0.61) | KDM4EGPR84MEN1KMT2APTPN5 | |
| SCHEMBL30958421 | 0.73 | ICMT (0.62) | KDM4EGPR84MEN1KMT2APTPN5 | |
| SCHEMBL588980 | 0.73 | ICMT (0.62) | KDM4EGPR84MEN1KMT2APTPN5 | |
| SCHEMBL29623198 | 0.73 | GPR84 (0.61) | KDM4EGPR84MEN1KMT2APTPN5 | |
| SCHEMBL15143088 | 0.72 | POLB (0.77) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL3155846 | 0.72 | ICMT (0.60) | KDM4EGPR84MEN1KMT2APTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218343-A4 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2003-06-18 | — | — | EP | disclosed |
| EP-1218343-A1 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001025203-A1 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-12 | — | — | WO | disclosed |