Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.48 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.48 |
| ▸ | F9 | P00740 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350713 | 1.00 | AURKA (0.56) | AURKAKDRAURKBRAB9APOLB | |
| SCHEMBL29623716 | 0.81 | AURKA (0.61) | AURKAKDRAURKBRAB9ANPC1 | |
| SCHEMBL19350812 | 0.81 | AURKA (0.61) | AURKAKDRAURKBRAB9ANPC1 | |
| SCHEMBL29623560 | 0.81 | TAAR1 (0.60) | AURKAKDRAURKBRAB9ANPC1 | |
| SCHEMBL19350760 | 0.81 | TAAR1 (0.60) | AURKAKDRAURKBRAB9ANPC1 | |
| SCHEMBL19350868 | 0.79 | AURKA (0.64) | AURKAKDRAURKBRAB9ANPC1 | |
| SCHEMBL20603923 | 0.78 | HTT (0.63) | AURKAKDRAURKBRAB9ANPC1 | |
| SCHEMBL18236206 | 0.77 | RAB9A (0.74) | RAB9APOLBNPC1SMN1; SMN2KMT2A | |
| SCHEMBL19350939 | 0.77 | NPC1 (0.57) | AURKAKDRAURKBRAB9ANPC1 | |
| SCHEMBL29623720 | 0.77 | NPC1 (0.57) | AURKAKDRAURKBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071523-B | Urea compound, preparation method and medical application thereof | 恩瑞生物医药科技（上海）有限公司 | 2022-05-31 | — | — | CN | disclosed |