SCHEMBL29623802

SCHEMBL29623802

CC(C)(C)c1ccccc1OP(O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
TDP1 Q9NUW8 2/20 0.45
TSHR P16473 1/20 0.45
ATM Q13315 1/20 0.45
MAPT P10636 2/20 0.42
NAMPT P43490 1/20 0.42
TP53 P04637 1/20 0.42
KDM4E B2RXH2 3/20 0.41
GAA P10253 1/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41
CA2 P00918 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B10 Q99714 1/20 0.40
BCHE P06276 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
P2RY1 P47900 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5009501 1.00 ALDH1A1 (0.45) ALDH1A1TDP1TSHRATMMAPT
SCHEMBL30675344 1.00 ALDH1A1 (0.45) ALDH1A1TDP1TSHRATMMAPT
SCHEMBL29660531 0.88 ALDH1A1 (0.35) ALDH1A1TDP1TSHRATMMAPT
SCHEMBL4277588 0.88 ALDH1A1 (0.35) ALDH1A1TDP1TSHRATMMAPT
SCHEMBL11254545 0.88 ALDH1A1 (0.45) ALDH1A1TDP1TSHRATMMAPT
Tromethamine SCHEMBL8351464 0.87 RXRA (0.40) ALDH1A1TDP1TSHRATMMAPT
SCHEMBL30909302 0.86 NAMPT (0.42) ALDH1A1TDP1TSHRATMMAPT
SCHEMBL30082448 0.86 TDP1 (0.41) ALDH1A1TDP1TSHRATMMAPT
SCHEMBL11309617 0.84 TDP1 (0.46) ALDH1A1TDP1TSHRATMMAPT
SCHEMBL380498 0.83 MAPT (0.44) ALDH1A1TDP1TSHRATMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3986875-A1 PHENOXYPHENYL HYDROXYISOXAZOLINES AND ANALOGUES AS NEW ANTIFUNGAL AGENTS Bayer Aktiengesellschaft (DE) 2022-04-27 EP disclosed