Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5390696 | 1.00 | ALDH1A1 (0.70) | ALDH1A1LTC4SRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6351301 | 0.93 | ALDH1A1 (0.61) | ALDH1A1LTC4SRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6905477 | 0.86 | ALDH1A1 (0.67) | ALDH1A1LTC4SRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6965655 | 0.86 | ALDH1A1 (0.71) | ALDH1A1LTC4SRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5888457 | 0.85 | ALDH1A1 (0.70) | ALDH1A1LTC4SRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6270813 | 0.82 | ALDH1A1 (0.65) | ALDH1A1LTC4SRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL14439883 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LTC4SRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL29355043 | 0.82 | ALDH1A1 (1.00) | ALDH1A1LTC4SRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7624466 | 0.82 | ALDH1A1 (1.00) | ALDH1A1LTC4SRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6964103 | 0.82 | ALDH1A1 (0.67) | ALDH1A1RAB9AKMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250000821-A1 | METHODS OF USING DIPIVEFRIN | Insignis Therapeutics, Inc. | 2025-01-02 | — | — | US | disclosed |
| CN-111565716-B | Method of using dipivefrin | 因斯格尼斯疗法有限公司 | 2023-06-09 | — | — | CN | disclosed |
| US-20220193010-A1 | METHODS OF USING DIPIVEFRIN | INSIGNIS THERAPEUTICS INC (US) | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250000821-A1 | METHODS OF USING DIPIVEFRIN | QDPR, DNPEP, DPEP1 | ALDH1A1 1423/4885LTC4S 1053/4885RAB9A 3101/4885 |
| US-20220193010-A1 | METHODS OF USING DIPIVEFRIN | QDPR, DNPEP, DPEP1 | ALDH1A1 1423/4885LTC4S 1053/4885RAB9A 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.