Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.59 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.53 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 2/20 | 0.50 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405906 | 0.94 | TASP1 (0.55) | BACE1ENPEPTASP1CTSDBACE2 | |
| SCHEMBL38660823 | 0.92 | TASP1 (0.61) | BACE1ENPEPTASP1CTSDBACE2 | |
| SCHEMBL30059944 | 0.92 | ENPEP (0.60) | BACE1ENPEPCTSDFOLH1 | |
| SCHEMBL31720926 | 0.92 | ENPEP (0.55) | BACE1ENPEPTASP1CTSDBACE2 | |
| SCHEMBL10621016 | 0.91 | TASP1 (0.59) | BACE1ENPEPTASP1CTSD | |
| SCHEMBL30491749 | 0.90 | NTSR2 (0.51) | BACE1ENPEPTASP1 | |
| SCHEMBL29630470 | 0.89 | ENPEP (0.58) | BACE1ENPEPTASP1CTSDBACE2 | |
| SCHEMBL31563685 | 0.89 | GRIN2D (0.59) | BACE1ENPEPTASP1CTSDBACE2 | |
| SCHEMBL29378835 | 0.89 | ENPEP (0.54) | BACE1ENPEPTASP1BACE2FOLH1 | |
| SCHEMBL29679591 | 0.88 | NTSR2 (0.52) | BACE1ENPEPCTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220218790-A1 | PARATHYROID HORMONE FUSION POLYPEPTIDE | UNIVERSITY OF SHEFFIELD (GB) | 2022-07-14 | — | — | US | claimed |
| CN-110546159-B | Parathyroid hormone fusion polypeptides | 谢菲尔德大学 | 2023-08-22 | — | — | CN | disclosed |
| US-20220218790-A1 | PARATHYROID HORMONE FUSION POLYPEPTIDE | UNIVERSITY OF SHEFFIELD (GB) | 2022-07-14 | — | — | US | disclosed |
| US-11344606-B2 | Parathyroid hormone fusion polypeptide | UNIVERSITY OF SHEFFIELD (GB) | 2022-05-31 | — | — | US | disclosed |