SCHEMBL29378835

SCHEMBL29378835

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nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ENPEP Q07075 9/20 0.54
▸ TASP1 Q9H6P5 1/20 0.49
▸ FOLH1 Q04609 2/20 0.49
▸ BACE1 P56817 7/20 0.49
▸ BACE2 Q9Y5Z0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29405906 0.96 TASP1 (0.55) ENPEPTASP1FOLH1BACE1BACE2
SCHEMBL30355008 0.91 ENPEP (0.58) ENPEPTASP1BACE1BACE2
SCHEMBL30163434 0.90 BACE1 (0.52) ENPEPTASP1FOLH1BACE1BACE2
SCHEMBL31491410 0.90 ENPEP (0.57) ENPEPTASP1BACE1
SCHEMBL30059944 0.90 ENPEP (0.60) ENPEPFOLH1BACE1
SCHEMBL29815897 0.89 FOLH1 (0.60) FOLH1BACE1BACE2
SCHEMBL29624626 0.89 BACE1 (0.59) ENPEPTASP1FOLH1BACE1BACE2
SCHEMBL31720926 0.89 ENPEP (0.55) ENPEPTASP1FOLH1BACE1BACE2
SCHEMBL31287158 0.89 ENPEP (0.54) ENPEPTASP1FOLH1BACE1
SCHEMBL30400303 0.88 ENPEP (0.53) ENPEPTASP1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209054-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2024-06-27 — — US disclosed
US-11814417-B2 GIP agonist compounds and methods ZEALAND PHARMA A/S (DK) 2023-11-14 — — US disclosed
US-20220041676-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2022-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209054-A1 GIP AGONIST COMPOUNDS AND METHODS GIPR, GLP1R, GPR119 ENPEP 214/4885TASP1 2699/4885FOLH1 913/4885
US-11814417-B2 GIP agonist compounds and methods GIPR, GLP1R, GPR119 ENPEP 214/4885TASP1 2699/4885FOLH1 913/4885
US-20220041676-A1 GIP AGONIST COMPOUNDS AND METHODS GIPR, GLP1R, GPR119 ENPEP 214/4885TASP1 2699/4885FOLH1 913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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