Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161457 | 1.00 | CYP11B1 (0.38) | CYP11B1CYP11B2HTTHRH3RAF1 | |
| SCHEMBL2560682 | 0.83 | ADORA2A (0.43) | CYP11B1CYP11B2HTTHRH3RAF1 | |
| SCHEMBL31446925 | 0.79 | CYP11B2 (0.47) | CYP11B1CYP11B2HTTHRH3RAF1 | |
| SCHEMBL1413419 | 0.79 | GRIN2B (0.40) | CYP11B1CYP11B2HRH3RAF1GRIN1 | |
| SCHEMBL30044994 | 0.79 | CYP11B1 (0.47) | CYP11B1CYP11B2HRH3RAF1GRIN1 | |
| SCHEMBL19911768 | 0.79 | CYP11B2 (0.47) | CYP11B1CYP11B2HTTHRH3RAF1 | |
| SCHEMBL1413347 | 0.79 | LOXL2 (0.48) | CYP11B1CYP11B2HTTHRH3RAF1 | |
| SCHEMBL7673123 | 0.79 | CYP11B1 (0.38) | CYP11B1CYP11B2HTTHRH3RAF1 | |
| SCHEMBL1413439 | 0.79 | CYP11B1 (0.47) | CYP11B1CYP11B2HRH3RAF1GRIN1 | |
| SCHEMBL29391958 | 0.79 | GRIN2B (0.40) | CYP11B1CYP11B2HRH3RAF1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444423-A1 | 3-((3-([1,1'-BIPHENYL]-3-YLMETHOXY)PHENOXY)METHYL)BENZONITRILE DERIVATIVES AND THE USE THEREOF | Helmholtz-Zentrum Dresden - Rossendorf e.V. (DE) | 2024-10-16 | — | — | EP | disclosed |
| CN-118715214-A | 3- ((3- ([ 1,1' -Biphenyl ] -3-ylmethoxy) -phenoxy) methyl) benzonitrile derivative and application thereof | 赫姆霍兹-森德拉姆德雷斯顿-罗森多夫研究中心 | 2024-09-27 | — | — | CN | disclosed |
| CN-117964559-A | 8-Phenylquinazoline compound and application thereof | 华侨大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| EP-4352060-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2023104744-A1 | 3-((3-([1,1'-BIPHENYL]-3-YLMETHOXY)PHENOXY)METHYL)BENZONITRILE DERIVATIVES AND THE USE THEREOF | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2023-06-15 | — | — | WO | disclosed |
| CN-115611889-A | PD-L1 inhibitor and preparation method and application thereof | 上海华汇拓医药科技有限公司 | 2023-01-17 | — | — | CN | disclosed |
| WO-2022261159-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION (US) | 2022-12-15 | — | — | WO | disclosed |
| CN-109803651-B | Immunomodulatory compounds | 凯莫森特里克斯股份有限公司 | 2022-05-31 | — | — | CN | disclosed |