Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.55 |
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24953240 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL29625786 | 0.83 | MEN1 (0.50) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL24953239 | 0.83 | MEN1 (0.50) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL152719 | 0.73 | TNF (0.65) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL3031458 | 0.73 | ALDH1A1 (0.78) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL12397237 | 0.70 | HTT (0.62) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL31558359 | 0.69 | KDM4E (0.50) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL36762 | 0.69 | HSD17B10 (1.00) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL29357214 | 0.69 | HSD17B10 (1.00) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL226196 | 0.69 | HSD17B10 (0.76) | KDM4EALDH1A1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114401935-A | Ion channel antagonists/blockers and uses thereof | 上海市东方医院（同济大学附属东方医院） | 2022-04-26 | — | — | CN | disclosed |