Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24953239 | 1.00 | MEN1 (0.50) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL24953240 | 0.83 | KDM4E (0.55) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL29625751 | 0.83 | KDM4E (0.55) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL28727071 | 0.80 | KMT2A (0.52) | MEN1KMT2AHTTTSHRALDH1A1 | |
| SCHEMBL28727021 | 0.72 | NPBWR1 (0.54) | MEN1KMT2AHTTTSHRALDH1A1 | |
| SCHEMBL8293061 | 0.71 | PLA2G2A (0.47) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL29620186 | 0.70 | MAPT (0.58) | MEN1KMT2AHTTKDM4EMAPT | |
| SCHEMBL702988 | 0.70 | MAPT (0.58) | MEN1KMT2AHTTKDM4EMAPT | |
| SCHEMBL19766698 | 0.70 | MAPT (0.62) | MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL6797257 | 0.69 | KMT2A (0.79) | MEN1KMT2AHTTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114401935-A | Ion channel antagonists/blockers and uses thereof | 上海市东方医院（同济大学附属东方医院） | 2022-04-26 | — | — | CN | disclosed |