Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29625882 | 1.00 | HSD17B10 (0.40) | HSD17B10TSHRLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL24540159 | 0.89 | CYP3A4 (0.43) | TSHRLMNAL3MBTL1KDM4ETDP1 | |
| SCHEMBL29625863 | 0.88 | RARA (0.42) | — | |
| SCHEMBL29625881 | 0.88 | ACACB (0.35) | HSD17B10TSHRL3MBTL1ALDH1A1HPGD | |
| SCHEMBL29625883 | 0.88 | ACACB (0.35) | HSD17B10TSHRL3MBTL1ALDH1A1HPGD | |
| SCHEMBL24540207 | 0.86 | KDM4E (0.33) | HSD17B10TSHRLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL17189716 | 0.85 | KDM4E (0.42) | HSD17B10LMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL704976 | 0.83 | TSHR (0.50) | HSD17B10TSHRLMNAL3MBTL1KDM4E | |
| SCHEMBL17189737 | 0.80 | ALDH1A1 (0.38) | HSD17B10L3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL17181394 | 0.80 | ALDH1A1 (0.36) | HSD17B10TSHRL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263749-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | Merck Patent GmbH (DE) | 2023-10-25 | — | — | EP | disclosed |
| CN-116670255-A | Dibenzofuran and dibenzothiophene derivatives | 默克专利股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022128847-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |