Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24540173 | 1.00 | MAOB (0.39) | MAOBMRGPRX4KDM4EKDM1ATACR2 | |
| SCHEMBL24540167 | 0.89 | MRGPRX4 (0.43) | MAOBMRGPRX4MAPK1MAPTPKM | |
| SCHEMBL17490422 | 0.87 | MAOB (0.47) | MAOBMRGPRX4KDM4EKDM1ATACR2 | |
| SCHEMBL17189716 | 0.85 | KDM4E (0.42) | KDM4EKDM1AMAPK1HSD17B10GAA | |
| SCHEMBL17490328 | 0.81 | FFAR1 (0.44) | MAOBMRGPRX4KDM1ATACR2MAPK1 | |
| SCHEMBL29625877 | 0.81 | SLC26A3 (0.39) | MAOBMRGPRX4KDM4EKDM1ATACR2 | |
| SCHEMBL24540009 | 0.81 | SLC26A3 (0.39) | MAOBMRGPRX4KDM4EKDM1ATACR2 | |
| SCHEMBL17189714 | 0.79 | KDM4E (0.40) | MRGPRX4KDM4EMAPK1HSD17B10GAA | |
| SCHEMBL29563616 | 0.78 | L3MBTL1 (0.41) | KDM4EKDM1AMAPK1HSD17B10GAA | |
| SCHEMBL30589501 | 0.78 | L3MBTL1 (0.41) | KDM4EKDM1AMAPK1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263749-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | Merck Patent GmbH (DE) | 2023-10-25 | — | — | EP | disclosed |
| CN-116670255-A | Dibenzofuran and dibenzothiophene derivatives | 默克专利股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022128847-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |