Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A3 | P40879 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24540009 | 1.00 | SLC26A3 (0.39) | SLC26A3MAOBKDM4EALDH1A1ACHE | |
| SCHEMBL17490422 | 0.87 | MAOB (0.47) | MAOBKDM4EMRGPRX4KDM1AL3MBTL1 | |
| SCHEMBL17641349 | 0.85 | ALDH1A1 (0.45) | KDM4EALDH1A1KDM1AHPGDHSD17B10 | |
| SCHEMBL30545647 | 0.82 | KDM4E (0.36) | KDM4EALDH1A1KDM1AHPGDHSD17B10 | |
| SCHEMBL18133460 | 0.82 | ALDH1A1 (0.41) | KDM4EALDH1A1KDM1AHPGDHSD17B10 | |
| SCHEMBL17490328 | 0.81 | FFAR1 (0.44) | MAOBALDH1A1MRGPRX4KDM1AHPGD | |
| SCHEMBL29625871 | 0.81 | MAOB (0.39) | MAOBKDM4EALDH1A1MRGPRX4KDM1A | |
| SCHEMBL24540173 | 0.81 | MAOB (0.39) | MAOBKDM4EALDH1A1MRGPRX4KDM1A | |
| SCHEMBL17641350 | 0.79 | ALDH1A1 (0.41) | KDM4EALDH1A1MRGPRX4HPGDHSD17B10 | |
| SCHEMBL19625889 | 0.79 | KDM4E (0.37) | SLC26A3KDM4EALDH1A1KDM1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263749-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | Merck Patent GmbH (DE) | 2023-10-25 | — | — | EP | disclosed |
| CN-116670255-A | Dibenzofuran and dibenzothiophene derivatives | 默克专利股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022128847-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |