Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10806950 | 0.98 | HTR1A (0.42) | HTR1AL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL14557432 | 0.98 | HTR1A (0.45) | HTR1AL3MBTL1MEN1KMT2ATDP1 | |
| Alanine SCHEMBL27722574 | 0.88 | HRH3 (0.39) | HTR1AL3MBTL1MEN1KMT2ATDP1 | |
| Alanine SCHEMBL27702174 | 0.85 | HRH3 (0.37) | HTR1AL3MBTL1HRH3 | |
| SCHEMBL26725202 | 0.83 | HRH3 (0.46) | L3MBTL1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL15904342 | 0.83 | HRH3 (0.41) | L3MBTL1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL12156805 | 0.81 | HTR1A (0.68) | HTR1ATDP1HRH3ALDH1A1POLB | |
| SCHEMBL1858027 | 0.80 | HTR1A (0.67) | HTR1AL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL14557427 | 0.79 | HTR1A (0.46) | HTR1APOLB | |
| SCHEMBL5958440 | 0.79 | CA2 (0.42) | HTR1AKMT2AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456175-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114456176-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |