Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345211 | 0.83 | HRH3 (0.46) | HRH3ALDH1A1 | |
| SCHEMBL29626142 | 0.83 | HTR1A (0.44) | HRH3ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9760358 | 0.81 | HRH3 (0.43) | HRH3 | |
| Hydrochloric Acid SCHEMBL10806950 | 0.81 | HTR1A (0.42) | HRH3ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL14557432 | 0.80 | HTR1A (0.45) | HRH3ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL26725202 | 0.79 | HRH3 (0.46) | HRH3ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL3347181 | 0.77 | HRH3 (0.40) | HRH3MEN1KMT2A | |
| SCHEMBL3263872 | 0.77 | HRH3 (0.43) | HRH3 | |
| SCHEMBL9760411 | 0.77 | HRH3 (0.44) | HRH3MAPTTSHRGFER | |
| SCHEMBL378130 | 0.77 | MAPT (0.52) | ALDH1A1MEN1KMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014113932-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-07-31 | — | — | WO | disclosed |