Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 2/20 | 0.44 |
| ▸ | KDM4B | O94953 | 2/20 | 0.44 |
| ▸ | KDM5C | P41229 | 2/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19692167 | 1.00 | GAA (0.47) | GAAMAPK1KDM4AKDM4BKDM5C | |
| SCHEMBL20971362 | 0.83 | PARP1 (0.42) | KDM4AKDM4BKDM5CKDM5BPARP1 | |
| SCHEMBL20971053 | 0.80 | SRC (0.55) | GAAMAPK1PARP1SMN1; SMN2PDPK1 | |
| SCHEMBL20971165 | 0.79 | TGFBR1 (0.47) | GAAPARP1SMN1; SMN2PDPK1CA12 | |
| SCHEMBL29630932 | 0.79 | TGFBR1 (0.47) | GAAPARP1SMN1; SMN2PDPK1CA12 | |
| SCHEMBL32668671 | 0.77 | PARP1 (0.43) | KDM4AKDM4BKDM5CKDM5BPARP1 | |
| SCHEMBL20586673 | 0.77 | GAA (0.47) | GAAMAPK1KDM4AKDM4BKDM5C | |
| SCHEMBL30219918 | 0.77 | GAA (0.47) | GAAMAPK1KDM4AKDM4BKDM5C | |
| SCHEMBL20971154 | 0.76 | ALOX5 (0.41) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL29630995 | 0.76 | ALOX5 (0.41) | PARP1SMN1; SMN2PDPK1CA12ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | claimed |
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |