Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105331 | 1.00 | KDM4E (0.56) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| Water SCHEMBL8810335 | 0.98 | KDM4E (0.54) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL29518264 | 0.86 | MAPT (0.56) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL3400912 | 0.86 | MAPT (0.56) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL1607899 | 0.84 | NLRP3 (0.53) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL30006017 | 0.84 | NLRP3 (0.53) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL29820797 | 0.83 | KDM4E (0.53) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL18132167 | 0.80 | CYP1A2 (0.58) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL6675330 | 0.80 | NLRP3 (0.64) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL10645020 | 0.80 | NLRP3 (0.60) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151304-B | Small molecule interferon gene stimulating factor (STING) antagonists | 库拉德夫制药私人有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-114929683-B | Pyridine derivatives as modulators of calcium activated chloride channels | 跨膜蛋白16A有限公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-4103278-A1 | SMALL MOLECULE STING ANTAGONISTS | Curadev Pharma Pvt. Ltd. (IN) | 2022-12-21 | — | — | EP | disclosed |
| CN-115151304-A | Small molecule interferon gene stimulating factor (STING) antagonists | 库拉德夫制药私人有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-115151540-A | Polyheterocyclic compounds as METTL3 inhibitors | 风暴治疗有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-114929683-A | Pyridine derivatives as calcium-activated chloride channel modulators | 跨膜蛋白16A有限公司 | 2022-08-19 | — | — | CN | disclosed |
| EP-4003977-A1 | PYRIDINE DERIVATIVES AS CALCIUM-ACTIVATED CHLORIDE CHANNEL MODULATORS | TMEM16A LIMITED (GB) | 2022-06-01 | — | — | EP | disclosed |