Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29627552 | 1.00 | KDM4E (0.56) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| Water SCHEMBL8810335 | 0.98 | KDM4E (0.54) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL29518264 | 0.86 | MAPT (0.56) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL3400912 | 0.86 | MAPT (0.56) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL1607899 | 0.84 | NLRP3 (0.53) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL30006017 | 0.84 | NLRP3 (0.53) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL29820797 | 0.83 | KDM4E (0.53) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL18132167 | 0.80 | CYP1A2 (0.58) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL6675330 | 0.80 | NLRP3 (0.64) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 | |
| SCHEMBL10645020 | 0.80 | NLRP3 (0.60) | KDM4EHPGDHSD17B10ALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122081247-A | Oncolytic vaccinia virus and recombinant viruses and methods of use thereof | — | 2026-05-26 | — | — | CN | disclosed |
| US-12606557-B2 | Substituted indoles with inhibitory activity | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2026-04-21 | — | — | US | disclosed |
| EP-4003977-B1 | PYRIDINE DERIVATIVES AS CALCIUM-ACTIVATED CHLORIDE CHANNEL MODULATORS | TMEM16A LTD (GB) | 2026-04-15 | — | — | EP | disclosed |
| US-12545658-B2 | Pyridine derivatives as calcium-activated chloride channel modulators | TMEM16A LIMITED (GB) | 2026-02-10 | — | — | US | disclosed |
| US-20250122195-A1 | POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS | STORM THERAPEUTICS LIMITED (GB) | 2025-04-17 | — | — | US | disclosed |
| CN-116554050-B | Amide phenol derivative and application thereof | 四川大学 | 2025-03-18 | — | — | CN | disclosed |
| US-12195458-B2 | Polyheterocyclic compounds as METTL3 inhibitors | STORM THERAPEUTICS LIMITED (GB) | 2025-01-14 | — | — | US | disclosed |
| EP-3573960-B1 | N-{[2-(PIPERIDIN-1-YL)PHENYL](PHENYL)METHYL}-2-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-YL)ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ROR-GAMMA MODULATORS FOR TREATING AUTOIMMUNE DISEASES | GENFIT (FR) | 2023-08-16 | — | — | EP | disclosed |
| US-11725010-B2 | Polyheterocyclic compounds as METTL3 inhibitors | STORM THERAPEUTICS LIMITED (GB) | 2023-08-15 | — | — | US | disclosed |
| US-11725010-B2 | Polyheterocyclic compounds as METTL3 inhibitors | STORM THERAPEUTICS LIMITED (GB) | 2023-08-15 | — | — | US | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |
| US-5439906-A | Antiarrhythmic benzodiazepines | MERCK & CO., INC. (US) | 1995-08-08 | — | — | US | disclosed |
| WO-1995014693-A1 | IMIDAZOLINOBENZODIAZEPINES | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| WO-1995014472-A1 | ANTIARRHYTHMIC BENZODIAZEPINES | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| EP-0290145-B1 | Aliphatic carboxamides | ICI AMERICA INC (US) | 1994-10-26 | — | — | EP | disclosed |
| US-5288749-A | Treating central nervous system or cardiovascular disorders | ABBOTT LABORATORIES (US) | 1994-02-22 | — | — | US | disclosed |
| WO-1993012754-A2 | TERTIARY AND SECONDARY AMINES AS ALPHA-2 ANTAGONISTS AND SEROTONIN UPTAKE INHIBITORS | ABBOTT LABORATORIES (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4894386-A | ANTIINFLAMMATORY AGENTS | ICI AMERICAS INC. (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0290145-A1 | Aliphatic carboxamides | ZENECA INC. (US) | 1988-11-09 | — | — | EP | disclosed |
| US-4242120-A | APPLYING A LOW MOLECULAR WEIGHT CARBOHYDRATE-CONTAINING MIXTURE TO A REPRODUCTIVE ZONE | SIMFEROPOLSKY GOSUDARSTVENNY UNIVERSITET IMENI M.V. (SU) | 1980-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122195-A1 | POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS | METTL3, DIMT1, TPMT | KDM4E 107/4885HPGD 4303/4885HSD17B10 3258/4885 |
| US-12545658-B2 | Pyridine derivatives as calcium-activated chloride channel modulators | CACNA1E, CACNA1D, CACNA1B | KDM4E 1939/4885HPGD 2613/4885HSD17B10 4107/4885 |
| US-12606557-B2 | Substituted indoles with inhibitory activity | IDO1, BCL9, IDO2 | KDM4E 1848/4885HPGD 1886/4885HSD17B10 570/4885 |
| US-11725010-B2 | Polyheterocyclic compounds as METTL3 inhibitors | METTL3, DIMT1, TPMT | KDM4E 107/4885HPGD 4303/4885HSD17B10 3258/4885 |
| US-12195458-B2 | Polyheterocyclic compounds as METTL3 inhibitors | METTL3, DIMT1, TPMT | KDM4E 107/4885HPGD 4303/4885HSD17B10 3258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.