SCHEMBL296278

SCHEMBL296278

NC(Cc1ccc(CO)cc1)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.71
PTGS1 P23219 3/20 0.70
ALPI P09923 1/20 0.70
PKM P14618 1/20 0.70
XIAP P98170 1/20 0.70
HIF1A Q16665 5/20 0.59
ALOX15 P16050 3/20 0.59
KDM4E B2RXH2 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
HSD17B10 Q99714 2/20 0.59
USP2 O75604 1/20 0.59
EGFR P00533 1/20 0.59
LCK P06239 1/20 0.59
FYN P06241 1/20 0.59
ADORA3 P0DMS8 1/20 0.59
HTR2A P28223 1/20 0.59
PTGS2 P35354 1/20 0.59
RECQL P46063 1/20 0.59
TPH1 P17752 1/20 0.59
GRB2 P62993 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216414 1.00 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL503768 1.00 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL2310526 0.91 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL27913268 0.88 SLC7A5 (0.77) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL16581271 0.85 SLC7A5 (0.74) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL156189 0.85 SLC7A5 (0.74) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL837014 0.85 SLC7A5 (0.74) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL1505730 0.84 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL28052750 0.84 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL3670851 0.83 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023042201-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2023-03-23 WO claimed
CN-105143245-B Anti-scaling material 耶路撒冷希伯来大学伊森姆研究发展有限公司 2021-02-05 CN claimed
EP-2951195-B1 ANTIFOULING MATERIALS YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD (IL) 2020-02-19 EP claimed
EP-3374520-A1 BIOSENSORS Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2018-09-19 EP claimed
WO-2017081684-A1 BIOSENSORS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2017-05-18 WO claimed
US-9631100-B2 Antifouling materials YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2017-04-25 US claimed
US-20150368480-A1 ANTIFOULING MATERIALS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2015-12-24 US claimed
EP-2951195-A1 ANTIFOULING MATERIALS Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. (IL) 2015-12-09 EP claimed
CN-105143245-A Anti-scaling material YISSUM RES DEV CO 2015-12-09 CN claimed
WO-2014118779-A1 ANTIFOULING MATERIALS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2014-08-07 WO claimed
US-20100183642-A1 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-07-22 US claimed
US-20100136034-A1 NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-06-03 US claimed
EP-2114998-A1 NOVEL MULTIMERIC MOLECULES, METHOD FOR PREPARING SAME AND USE THEREOF IN THE PREPARATION OF DRUGS Centre National de la Recherche Scientifique (FR) 2009-11-11 EP claimed
EP-1828240-B1 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CENTRE NAT RECH SCIENT (FR) 2009-07-29 EP claimed
WO-2008110695-A1 NOVEL MULTIMERIC MOLECULES, METHOD FOR PREPARING SAME AND USE THEREOF IN THE PREPARATION OF DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2008-09-18 WO claimed
EP-1828240-A2 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS The Centre National de la Recherche Scientifique (FR) 2007-09-05 EP claimed
WO-2006064133-A2 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2006-06-22 WO claimed
EP-1282418-B1 USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY APPLIED RESEARCH SYSTEMS (AN) 2005-08-17 EP claimed
US-6914069-B2 Pharmaceutically active compounds and methods of use APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2005-07-05 US claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100183642-A1 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CD40, CD40LG, TNFSF10 SLC7A5 1065/4885PTGS1 2032/4885ALPI 4495/4885
US-20100136034-A1 NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS TNFRSF1A, TNFRSF9, CD40 SLC7A5 1624/4885PTGS1 2481/4885ALPI 4621/4885
US-20150368480-A1 ANTIFOULING MATERIALS PFAS, FLNB, FLNA SLC7A5 2272/4885PTGS1 2521/4885ALPI 4730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.