SCHEMBL503768

SCHEMBL503768

N[C@H](Cc1ccc(CO)cc1)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.71
PTGS1 P23219 3/20 0.70
ALPI P09923 1/20 0.70
PKM P14618 1/20 0.70
XIAP P98170 1/20 0.70
HIF1A Q16665 5/20 0.59
ALOX15 P16050 3/20 0.59
KDM4E B2RXH2 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
HSD17B10 Q99714 2/20 0.59
USP2 O75604 1/20 0.59
EGFR P00533 1/20 0.59
LCK P06239 1/20 0.59
FYN P06241 1/20 0.59
ADORA3 P0DMS8 1/20 0.59
HTR2A P28223 1/20 0.59
PTGS2 P35354 1/20 0.59
RECQL P46063 1/20 0.59
TPH1 P17752 1/20 0.59
GRB2 P62993 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216414 1.00 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL296278 1.00 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL2310526 0.91 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL27913268 0.88 SLC7A5 (0.77) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL16581271 0.85 SLC7A5 (0.74) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL156189 0.85 SLC7A5 (0.74) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL837014 0.85 SLC7A5 (0.74) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL1505730 0.84 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL28052750 0.84 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL3670851 0.83 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11274126-B2 pH-sensitive cyclic peptides UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2022-03-15 US claimed
EP-3432908-A1 pH-SENSITIVE PEPTIDES Rhode Island Council on Postsecondary Education (US) 2019-01-30 EP claimed
WO-2017165452-A1 pH-SENSITIVE PEPTIDES RHODE ISLAND COUNCIL ON POSTSECONDARY EDUCATION (US) 2017-09-28 WO claimed
WO-2026107097-A1 SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF ENLAZA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
US-12630808-B2 Modified archaeal family b polymerases Singular Genomics Systems, Inc. (US) 2026-05-19 US disclosed
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES SINGULAR GENOMICS SYSTEMS INC (US) 2026-05-07 US disclosed
US-20260085299-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF SINGULAR GENOMICS SYSTEMS INC (US) 2026-03-26 US disclosed
US-12564644-B2 Cyclodextrin complexes of specialized proresolving mediators THETIS PHARMACEUTICALS LLC (US) 2026-03-03 US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
US-20250381270-A1 ISOLATING ACTIVE T-CELL CARS FROM BULK TRANSDUCED HUMAN T-CELLS UNIV CALIFORNIA (US) 2025-12-18 US disclosed
US-20250353926-A1 CROSSLINKING MULTISPECIFIC ANTIBODIES ENLAZA THERAPEUTICS INC (US) 2025-11-20 US disclosed
WO-2017210604-A1 COMPOSITIONS AND METHODS RELATING TO SALTS OF SPECIALIZED PRO-RESOLVING MEDIATORS OF INFLAMMATION THETIS PHARMACEUTICALS LLC (US) 2017-12-07 WO disclosed
WO-2017165452-A1 pH-SENSITIVE PEPTIDES RHODE ISLAND COUNCIL ON POSTSECONDARY EDUCATION (US) 2017-09-28 WO disclosed
US-9540620-B2 Methods and compositions for modulating G-alpha-Q signaling THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2017-01-10 US disclosed
WO-2016201007-A1 STABILIZED MINIMAL COILED-COIL MIMETICS NEW YORK UNIVERSITY (US) 2016-12-15 WO disclosed
US-20150218538-A1 Methods and Compositions for Modulating G-Alpha-Q Signaling NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-08-06 US disclosed
US-20150218137-A1 PYRAZOLYL-UREAS AS KINASE INHIBITORS OXULAR ACQUISITIONS LIMITED (GB) 2015-08-06 US disclosed
US-8445678-B2 2-quinoxalinol salen compounds and uses thereof AUBURN UNIVERSITY (US) 2013-05-21 US disclosed
US-20120028362-A1 2-QUINOXALINOL SALEN COMPOUNDS AND USES THEREOF AUBURN UNIVERSITY (US) 2012-02-02 US disclosed
US-20090286968-A1 2-Quinoxalinol Salen Compounds and Uses Thereof AUBURN UNIVERSITY (US) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11274126-B2 pH-sensitive cyclic peptides VIP, PHLPP1, PHLPP2 SLC7A5 227/4885PTGS1 2023/4885ALPI 1981/4885
US-12630808-B2 Modified archaeal family b polymerases SSU72, POLB, POLQ SLC7A5 318/4885PTGS1 4524/4885ALPI 207/4885
US-20150218137-A1 PYRAZOLYL-UREAS AS KINASE INHIBITORS SYK, BTK, LYN SLC7A5 4487/4885PTGS1 587/4885ALPI 741/4885
US-20090286968-A1 2-Quinoxalinol Salen Compounds and Uses Thereof NQO1, NQO2, SQOR SLC7A5 670/4885PTGS1 2501/4885ALPI 3470/4885
US-20250381270-A1 ISOLATING ACTIVE T-CELL CARS FROM BULK TRANSDUCED HUMAN T-CELLS PBK, CD4, ICOS SLC7A5 3423/4885PTGS1 4395/4885ALPI 4037/4885
US-20250353926-A1 CROSSLINKING MULTISPECIFIC ANTIBODIES FCGR3B, FCGR2A, CD22 SLC7A5 949/4885PTGS1 4749/4885ALPI 3154/4885
US-20120028362-A1 2-QUINOXALINOL SALEN COMPOUNDS AND USES THEREOF NQO1, NQO2, SQOR SLC7A5 670/4885PTGS1 2501/4885ALPI 3470/4885
US-20260085299-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF POLB, POLM, POLRMT SLC7A5 1762/4885PTGS1 2750/4885ALPI 378/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 SLC7A5 3352/4885PTGS1 842/4885ALPI 4755/4885
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES DNMT3A, POLB, POLM SLC7A5 1054/4885PTGS1 3561/4885ALPI 724/4885
US-12564644-B2 Cyclodextrin complexes of specialized proresolving mediators ALOX15, ALOX12, PTGES SLC7A5 2132/4885PTGS1 26/4885ALPI 3803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.