Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12384956 | 1.00 | ERN1 (0.38) | ERN1CYP2C9CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL19682346 | 0.86 | CYP2C9 (0.40) | ERN1CYP2C9CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL29954742 | 0.86 | CYP2C9 (0.40) | ERN1CYP2C9CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL1197434 | 0.82 | CYP2C9 (0.45) | ERN1CYP2C9CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL1311843 | 0.80 | ALDH1A1 (0.39) | ERN1CYP3A4ALDH1A1TSHRTDP2 | |
| SCHEMBL19682803 | 0.78 | ALDH1A1 (0.41) | ERN1CYP2C9CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL26110125 | 0.78 | ERN1 (0.43) | ERN1CYP2C9CYP3A4CYP2C19AR | |
| SCHEMBL15748351 | 0.78 | ERN1 (0.38) | ERN1CYP2C9CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL10290089 | 0.78 | CYP3A4 (0.36) | ERN1CYP2C9CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL828218 | 0.78 | ALDH1A1 (0.37) | ERN1CYP2C9CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587437-A1 | CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | Boundless Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-118488945-A | Sulfonamide ribonucleotide reductase (RNR) inhibitors and uses thereof | 无界生物公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-118434417-A | Cyclic sulfonamide ribonucleotide reductase (RNR) inhibitors and uses thereof | 无界生物公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-111386260-B | Sulfonamide compounds and uses thereof | 大鹏药品工业株式会社 | 2024-04-30 | — | — | CN | disclosed |
| WO-2024059563-A1 | CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| CN-109563057-B | Sulfonamide compound or salt thereof | 大鹏药品工业株式会社 | 2022-06-24 | — | — | CN | disclosed |