SCHEMBL19682346

SCHEMBL19682346

Cc1c(F)ccc(F)c1C=O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
ERN1 O75460 3/20 0.35
ALDH1A1 P00352 5/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2A6 P11509 1/20 0.33
DAO P14920 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31
AR P10275 1/20 0.31
TSHR P16473 1/20 0.31
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954742 1.00 CYP2C9 (0.40) CYP2C9CYP3A4CYP2C19ERN1ALDH1A1
SCHEMBL12384956 0.86 ERN1 (0.38) CYP2C9CYP3A4CYP2C19ERN1ALDH1A1
SCHEMBL29628640 0.86 ERN1 (0.38) CYP2C9CYP3A4CYP2C19ERN1ALDH1A1
SCHEMBL15748351 0.82 ERN1 (0.38) CYP2C9CYP3A4CYP2C19ERN1ALDH1A1
SCHEMBL26110125 0.82 ERN1 (0.43) CYP2C9CYP3A4CYP2C19ERN1MEN1
SCHEMBL10290089 0.82 CYP3A4 (0.36) CYP2C9CYP3A4CYP2C19ERN1ALDH1A1
SCHEMBL19682803 0.82 ALDH1A1 (0.41) CYP2C9CYP3A4CYP2C19ERN1ALDH1A1
SCHEMBL19481423 0.82 CYP3A4 (0.33) CYP2C9CYP3A4CYP2C19ERN1ALDH1A1
SCHEMBL12235261 0.81 ERN1 (0.42) CYP2C9CYP3A4CYP2C19ERN1ALDH1A1
SCHEMBL20872891 0.81 CYP3A4 (0.41) CYP2C9CYP3A4CYP2C19ERN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 US disclosed
WO-2025090412-A1 DCAF1 LIGANDS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2025-05-01 WO disclosed
WO-2024092009-A1 PROTEIN DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2024-05-02 WO disclosed
WO-2024092011-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2024-05-02 WO disclosed
US-10889555-B2 Sulfonamide compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2021-01-12 US disclosed
US-20200405697-A1 Antitumor Agent TAIHO PHARMACEUTICAL CO., LTD. (JP) 2020-12-31 US disclosed
US-20200399235-A1 Sulfonamide Compound or Salt Thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2020-12-24 US disclosed
EP-3718545-A1 ANTITUMOR AGENT Taiho Pharmaceutical Co., Ltd. (JP) 2020-10-07 EP disclosed
US-20200157066-A1 Sulfonamide Compound or Salt Thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2020-05-21 US disclosed
EP-3466934-A1 SULFONAMIDE COMPOUND OR SALT THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2019-04-10 EP disclosed
WO-2017209155-A1 SULFONAMIDE COMPOUND OR SALT THEREOF 大鵬薬品工業株式会社 2017-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200399235-A1 Sulfonamide Compound or Salt Thereof RNASEH1, SNRPA1, RRM2 CYP2C9 2356/4885CYP3A4 1514/4885CYP2C19 2072/4885
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF STAT6, NCOR2, NCOR1 CYP2C9 1513/4885CYP3A4 567/4885CYP2C19 2258/4885
US-20200157066-A1 Sulfonamide Compound or Salt Thereof RNASEH1, SNRPA1, RRM2 CYP2C9 2356/4885CYP3A4 1514/4885CYP2C19 2072/4885
US-10889555-B2 Sulfonamide compound or salt thereof RNASEH1, SNRPA1, RRM2 CYP2C9 2356/4885CYP3A4 1514/4885CYP2C19 2072/4885
US-20200405697-A1 Antitumor Agent HNRNPR, RRM2, RRM2B CYP2C9 3523/4885CYP3A4 2058/4885CYP2C19 3733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.