Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759025 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPK1MAPTHPGDTUBB1 | |
| SCHEMBL2588646 | 0.86 | MAPT (0.55) | ALDH1A1MAPK1MAPTHPGDTUBB1 | |
| SCHEMBL2306018 | 0.86 | TUBB1 (0.47) | ALDH1A1HPGDTUBB1TSHR | |
| SCHEMBL20607231 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPK1MAPTHPGDTUBB1 | |
| SCHEMBL29628684 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPK1MAPTHPGDTUBB1 | |
| SCHEMBL30122857 | 0.79 | ALDH1A1 (0.63) | ALDH1A1MAPK1MAPTHPGDTUBB1 | |
| SCHEMBL29803132 | 0.79 | TUBB1 (0.50) | ALDH1A1MAPK1MAPTHPGDTUBB1 | |
| SCHEMBL524712 | 0.79 | ALDH1A1 (0.63) | ALDH1A1MAPK1MAPTHPGDTUBB1 | |
| SCHEMBL1766183 | 0.79 | TUBB1 (0.50) | ALDH1A1MAPK1MAPTHPGDTUBB1 | |
| SCHEMBL12552993 | 0.79 | SRC (0.49) | ALDH1A1MAPK1MAPTHPGDTUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665339-A1 | INHIBITING ALPHA V BETA 8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| EP-4665458-A1 | INHIBITING ALPHA V BETA8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173570-A1 | INHIBITING αvβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |
| WO-2024173572-A1 | INHIBITING α vβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |