Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924383 | 0.79 | SIRT1 (0.47) | SIRT1SIRT2KDM1ABCHESIRT3 | |
| SCHEMBL6975852 | 0.78 | RORC (0.45) | SIRT1SIRT2KDM1ARORC | |
| SCHEMBL6975655 | 0.75 | MAPT (0.45) | TDP1RORC | |
| SCHEMBL31404944 | 0.74 | KDM1A (0.42) | SIRT1SIRT2KDM1ABCHESIRT3 | |
| SCHEMBL31561707 | 0.74 | TP53 (0.41) | SIRT1SIRT2KDM1ABCHEHDAC1 | |
| SCHEMBL925973 | 0.74 | POLB (0.49) | SIRT1SIRT2SIRT3 | |
| SCHEMBL29628751 | 0.73 | KDM1A (0.39) | SIRT1SIRT2KDM1ABCHEHDAC1 | |
| SCHEMBL23228659 | 0.71 | USP30 (0.43) | KDM1ABCHEHDAC1HDAC6USP30 | |
| SCHEMBL3540362 | 0.71 | NOTUM (0.64) | KDM1AHDAC1HDAC6USP30 | |
| SCHEMBL29628537 | 0.71 | NOTUM (0.64) | KDM1AHDAC1HDAC6USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563057-B | Sulfonamide compound or salt thereof | 大鹏药品工业株式会社 | 2022-06-24 | — | — | CN | disclosed |