Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19682451 | 0.79 | NOTUM (0.47) | KDM1ASTSHDAC1HDAC6BCHE | |
| SCHEMBL30812954 | 0.79 | NOTUM (0.47) | KDM1ASTSHDAC1HDAC6BCHE | |
| SCHEMBL29628564 | 0.73 | DRD2 (0.32) | SIRT1 | |
| SCHEMBL29628720 | 0.73 | SIRT1 (0.42) | KDM1ASTSHDAC1HDAC6BCHE | |
| SCHEMBL31443362 | 0.72 | UCHL1 (0.48) | KDM1ASTSHDAC1HDAC6BCHE | |
| SCHEMBL25980404 | 0.70 | UCHL1 (0.43) | KDM1AHDAC1HDAC6BCHENR1H2 | |
| SCHEMBL14587287 | 0.69 | KDM1A (0.46) | KDM1AHDAC1HDAC6BCHERORC | |
| SCHEMBL29628441 | 0.68 | HTR6 (0.31) | — | |
| SCHEMBL3205346 | 0.68 | UCHL1 (0.44) | KDM1AHDAC1HDAC6BCHENR1H2 | |
| SCHEMBL30479646 | 0.68 | UCHL1 (0.44) | KDM1AHDAC1HDAC6BCHENR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563057-B | Sulfonamide compound or salt thereof | 大鹏药品工业株式会社 | 2022-06-24 | — | — | CN | disclosed |