Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607349 | 1.00 | ERN1 (0.39) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL31573662 | 0.84 | PRKDC (0.43) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL23414419 | 0.83 | ERN1 (0.40) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL27189181 | 0.82 | ALDH1A1 (0.42) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL4655024 | 0.82 | ALDH1A1 (0.42) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL31573667 | 0.80 | TRPV4 (0.37) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL5759448 | 0.79 | PRKDC (0.44) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL27189236 | 0.79 | ERN1 (0.47) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL310426 | 0.79 | ALDH1A1 (0.42) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL31166894 | 0.79 | ALDH1A1 (0.42) | ERN1ALDH1A1KDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779076-B | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2022-05-03 | — | — | CN | disclosed |