Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 11/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310426 | 0.88 | ALDH1A1 (0.42) | ALDH1A1KDM4ETSHRTDP1CA1 | |
| SCHEMBL4655024 | 0.88 | ALDH1A1 (0.42) | ALDH1A1KDM4ETSHRTDP1CA1 | |
| SCHEMBL27581741 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KDM4ETSHRTDP1CA1 | |
| SCHEMBL5759448 | 0.84 | PRKDC (0.44) | ALDH1A1KDM4ETSHRTDP1CA1 | |
| SCHEMBL17263379 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL31166894 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KDM4ETSHRTDP1CA1 | |
| SCHEMBL7380240 | 0.82 | ERN1 (0.47) | CA1CA2ERN1TRIM24TYR | |
| SCHEMBL29628787 | 0.82 | ERN1 (0.39) | ALDH1A1KDM4ETSHRTDP1CA1 | |
| SCHEMBL20607349 | 0.82 | ERN1 (0.39) | ALDH1A1KDM4ETSHRTDP1CA1 | |
| SCHEMBL5656538 | 0.82 | MCL1 (0.44) | ALDH1A1KDM4ETSHRTDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270762-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | SPRING MILL PHARMA, INC. | 2024-08-15 | — | — | US | disclosed |
| EP-4347607-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-117693511-A | Penicillin binding protein inhibitors | 维纳拓尔斯制药公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-101085743-B | Fluorine-containing alkoxy combretastatin derivative, preparation method and use thereof | DADE PHARMACEUTICAL CO., LTD., ZHEJIANG PROV. (CN) | 2012-02-15 | — | — | CN | disclosed |
| CN-101085743-A | Fluorine-containing alkoxy combretastatin derivative, preparation method and use thereof | ZHEJIANG DADE PHARMACEUTICAL C (CN) | 2007-12-12 | — | — | CN | disclosed |
| CN-1142914-C | New phenanthridines | ��̹��ҽҩ��˾ | 2004-03-24 | — | — | CN | disclosed |
| CN-1214681-A | New phenanthridines | BYK GULDEN LOMBERG CHEM FAB (DE) | 1999-04-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270762-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | PEPD, BPGM, EBPL | ALDH1A1 2794/4885KDM4E 2087/4885TSHR 4262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.