SCHEMBL29628971

SCHEMBL29628971

CC(C)c1ccc(-c2cccc(-c3ccc(C(C)C)cc3)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.53
RXRB P28702 1/20 0.53
RXRG P48443 1/20 0.53
PTPN5 P54829 3/20 0.53
MEN1 O00255 1/20 0.48
ESR1 P03372 1/20 0.48
KMT2A Q03164 1/20 0.48
PTGS2 P35354 4/20 0.43
CYP17A1 P05093 1/20 0.43
KIF11 P52732 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
ABL1 P00519 2/20 0.42
ABCB1 P08183 2/20 0.42
BCR P11274 2/20 0.42
APP P05067 1/20 0.41
CA12 O43570 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10598462 0.95 RXRA (0.55) RXRARXRBRXRGPTPN5MEN1
SCHEMBL597362 0.92 PTPN5 (0.49) RXRARXRBRXRGPTPN5MEN1
SCHEMBL29727265 0.91 RXRA (0.65) RXRARXRBRXRGPTPN5PTGS2
SCHEMBL5355878 0.91 RXRA (0.65) RXRARXRBRXRGPTPN5PTGS2
SCHEMBL13523299 0.87 TAAR1 (0.55) RXRARXRBRXRGPTPN5TAAR1
Isopropylbenzene SCHEMBL28491864 0.85 RXRA (0.53) RXRARXRBRXRGPTPN5PTGS2
SCHEMBL10022337 0.85 HSD17B1 (0.68) RXRARXRBRXRGPTPN5MEN1
SCHEMBL12406121 0.85 TAAR1 (0.62) RXRARXRBRXRGPTPN5CYP17A1
SCHEMBL27665946 0.85 PTPN5 (0.46) RXRARXRBRXRGPTPN5MEN1
SCHEMBL12919966 0.85 MAOA (0.59) RXRARXRBRXRGPTPN5MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621045-A Method for synthesizing polyaromatic hydrocarbon from aryl formaldehyde 长沙资材科技有限公司 2022-06-14 CN disclosed