SCHEMBL29629341

SCHEMBL29629341

CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)C1CCCN1C(=O)[C@@H](N)CCCNC(=N)N)C(C)C)C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 6/20 0.68
▸ NPY2R P49146 8/20 0.67
▸ NPY4R P50391 8/20 0.67
▸ NPY5R Q15761 8/20 0.67
▸ NPY1R P25929 6/20 0.67
▸ KDM1A O60341 2/20 0.64
▸ NMUR2 Q9GZQ4 1/20 0.63
▸ NMUR1 Q9HB89 1/20 0.63
▸ CXCR4 P61073 2/20 0.63
▸ MAOB P27338 1/20 0.62
▸ KDM5A P29375 1/20 0.62
▸ KDM1B Q8NB78 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29533701 1.00 TFPI (0.68) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL29424820 1.00 TFPI (0.68) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL29973299 0.99 TFPI (0.66) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30017187 0.92 NPY2R (0.64) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL31121841 0.92 NMUR2 (0.68) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL29625796 0.91 KDM1A (0.66) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30176437 0.91 TFPI (0.64) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30176414 0.91 TFPI (0.64) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30432104 0.91 TFPI (0.69) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL29625797 0.91 TFPI (0.66) TFPINPY2RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4691556-A2 HUMANIZED ANTI-ACTH ANTIBODIES AND USE THEREOF H. Lundbeck A/S (DK) 2026-02-11 — — EP disclosed
EP-3835319-B1 HUMANIZED ANTI-ACTH ANTIBODIES AND USE THEREOF H LUNDBECK AS (DK) 2025-11-19 — — EP disclosed
EP-3315968-B1 UNIVERSAL ANTIGEN RETRIEVAL COMPOUNDS AND METHODS OF USE UNIV HOUSTON SYSTEM (US) 2025-10-15 — — EP disclosed
US-12428475-B2 Humanized anti-ACTH antibodies and use thereof H. LUNDBECK A/S (DK) 2025-09-30 — — US disclosed
US-12351627-B2 Anti-ACTH antibodies and use thereof H. LUNDBECK A/S (DK) 2025-07-08 — — US disclosed
WO-2025085293-A1 SOLVENT FREE RESORBABLE RESIN FOR 3D PRINTING DUKE UNIVERSITY (US) 2025-04-24 — — WO disclosed
CN-119719839-A Photovoltaic power generation power working condition data generation method based on improved diffusion model 南方电网新型电力系统(北京)研究院有限公司 2025-03-28 — — CN disclosed
CN-114430857-B Ion trap mass spectrometer, mass spectrometry method, and computer readable medium storing control program 株式会社岛津制作所 2025-02-25 — — CN disclosed
US-20240309065-A1 SHORT APOC-II MIMETIC PEPTIDES AND METHODS OF USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2024-09-19 — — US disclosed
US-20240165127-A1 CONTRAST AGENT FOR DIAGNOSIS OF VASCULAR DISEASE CONTAINING GADOLINIUM-BASED COMPOUND AS ACTIVE INGREDIENT AND SYNTHESIS METHOD THEREFOR DAEGU CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION (KR) 2024-05-23 — — US disclosed
EP-4359432-A2 SHORT APOC-II MIMETIC PEPTIDES AND METHODS OF USE The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2024-05-01 — — EP disclosed
CN-117580857-A APOC-II short mimetic peptides and methods of use 美国政府(由卫生和人类服务部的部长所代表) 2024-02-20 — — CN disclosed
US-11887833-B2 Ion trap mass spectrometer, mass spectrometry method and non-transitory computer readable medium storing control program SHIMADZU CORPORATION (JP) 2024-01-30 — — US disclosed
US-20230174641-A1 ANTI-ACTH ANTIBODIES AND USE THEREOF H LUNDBECK AS (DK) 2023-06-08 — — US disclosed
WO-2022271814-A2 SHORT APOC-II MIMETIC PEPTIDES AND METHODS OF USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-12-29 — — WO disclosed
US-20220277951-A1 ION TRAP MASS SPECTROMETER, MASS SPECTROMETRY METHOD AND NON-TRANSITORY COMPUTER READABLE MEDIUM STORING CONTROL PROGRAM SHIMADZU CORPORATION (JP) 2022-09-01 — — US disclosed
US-11427631-B2 Anti-ACTH antibodies and use thereof H. LUNDBECK A/S (DK) 2022-08-30 — — US disclosed
CN-114430857-A Ion trap mass spectrometer, mass spectrometry method, and control program 株式会社岛津制作所 2022-05-03 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351627-B2 Anti-ACTH antibodies and use thereof CRH, MC2R, GIPR TFPI 4870/4885NPY2R 250/4885NPY4R 87/4885
US-20230174641-A1 ANTI-ACTH ANTIBODIES AND USE THEREOF CRH, MC2R, GIPR TFPI 4870/4885NPY2R 250/4885NPY4R 87/4885
US-11427631-B2 Anti-ACTH antibodies and use thereof CRH, MC2R, GIPR TFPI 4870/4885NPY2R 250/4885NPY4R 87/4885
US-20240165127-A1 CONTRAST AGENT FOR DIAGNOSIS OF VASCULAR DISEASE CONTAINING GADOLINIUM-BASED COMPOUND AS ACTIVE INGREDIENT AND SYNTHESIS METHOD THEREFOR CTRL, CELA1, PRSS1 TFPI 254/4885NPY2R 3234/4885NPY4R 2681/4885
US-12428475-B2 Humanized anti-ACTH antibodies and use thereof CRH, MC2R, CRHR1 TFPI 4802/4885NPY2R 275/4885NPY4R 98/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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