Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.37 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22366382 | 0.91 | KDM4C (0.42) | KDM4COPRM1PIK3CDPIK3R2PIK3CA | |
| SCHEMBL29629580 | 0.88 | OPRM1 (0.43) | KDM4COPRM1PIK3CDPIK3R2PIK3CA | |
| SCHEMBL22637693 | 0.84 | KMT2A (0.46) | PIK3CDKMT2ANR3C2PKMHCAR3 | |
| SCHEMBL22637999 | 0.84 | HCAR3 (0.43) | PIK3CDKMT2ANR3C2PKMHCAR3 | |
| SCHEMBL26690735 | 0.83 | KMT2A (0.45) | PIK3CDKMT2ANR3C2PKMHCAR3 | |
| SCHEMBL22320386 | 0.81 | HSD11B1 (0.41) | KDM4CPIK3CDPIK3CAKMT2ANR3C2 | |
| SCHEMBL17437926 | 0.81 | HCAR3 (0.41) | KMT2ANR3C2PKMHCAR3 | |
| SCHEMBL22125893 | 0.79 | OPRM1 (0.40) | KDM4COPRM1PIK3CDPIK3R2PIK3CA | |
| SCHEMBL22319884 | 0.74 | F2 (0.40) | KDM4COPRM1KMT2APOLB | |
| SCHEMBL25564438 | 0.74 | CNR2 (0.39) | KDM4COPRM1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169645-A1 | COMPOUNDS AS BRUTON TYROSINE KINASE INHIBITORS, PREPARATION METHODS AND MEDICAL APPLICATIONS THEREOF | Eternity Bioscience Inc. | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169645-A1 | COMPOUNDS AS BRUTON TYROSINE KINASE INHIBITORS, PREPARATION METHODS AND MEDICAL APPLICATIONS THEREOF | BTK, LYN, LCK | KDM4C 2209/4885OPRM1 4024/4885PIK3CD 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.