Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.59 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 5/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547132 | 1.00 | FAAH (0.59) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL77261 | 1.00 | FAAH (0.59) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL304723 | 1.00 | FAAH (0.59) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL546219 | 1.00 | FAAH (0.59) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL4880167 | 1.00 | FAAH (0.59) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL303807 | 1.00 | FAAH (0.59) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL77270 | 1.00 | FAAH (0.59) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL4880544 | 1.00 | FAAH (0.59) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL301132 | 1.00 | FAAH (0.59) | FAAHCA2TSHRTHRBCES1 | |
| SCHEMBL303667 | 1.00 | FAAH (0.59) | FAAHCA2TSHRTHRBCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 908 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103464049-A | Perfluorohexyl sulfonyloxy benzyl cation surfactant as well as preparation method and application thereof | UNIV HUAZHONG NORMAL | 2013-12-25 | — | — | CN | claimed |
| CN-103432708-A | Perfluoro-hexyl sulphonyl oxygen benzyl amine oxide surface active agent as well asand preparation method and application thereof | UNIV HUAZHONG NORMAL | 2013-12-11 | — | — | CN | claimed |
| US-8492390-B2 | Synthesis of locked nucleic acid derivatives | SANTARIS PHARMA A/S (DK) | 2013-07-23 | — | — | US | claimed |
| US-8084458-B2 | Synthesis of locked nucleic acid derivatives | SANTARIS PHARMA A/S (DK) | 2011-12-27 | — | — | US | claimed |
| US-20100216983-A1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | SANTARIS PHARMA A/S, a Denmark corporation | 2010-08-26 | — | — | US | claimed |
| US-7619095-B2 | Process for the preparation of indolone derivative | ALEMBIC LIMITED (IN) | 2009-11-17 | — | — | US | claimed |
| EP-1848691-B1 | PROCESS FOR THE PREPARATION OF INDOLONE DERIVATIVE | ALEMBIC LTD (IN) | 2009-11-11 | — | — | EP | claimed |
| US-7569575-B2 | Formed via intermediates which are reactive with nucleophiles | SANTARIS PHARMA A/S (DK) | 2009-08-04 | — | — | US | claimed |
| EP-1845088-B1 | An improved process for the preparation of aripipirazole | RANBAXY LAB LTD (IN) | 2009-07-22 | — | — | EP | claimed |
| US-20080262244-A1 | Process for the Preparation of Indolone Derivative | ALEMBIC LIMITED (IN) | 2008-10-23 | — | — | US | claimed |
| EP-1848691-A1 | PROCESS FOR THE PREPARATION OF INDOLONE DERIVATIVE | Alembic Limited (IN) | 2007-10-31 | — | — | EP | claimed |
| EP-1845088-A1 | An improved process for the preparation of aripipirazole | Ranbaxy Laboratories Limited (IN) | 2007-10-17 | — | — | EP | claimed |
| US-20070238876-A1 | PROCESS FOR THE PREPARATION OF ARIPIPRAZOLE | RANBAXY LABORATORIES LIMITED (IN) | 2007-10-11 | — | — | US | claimed |
| EP-1501848-B1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | SANTARIS PHARMA AS (DK) | 2007-08-08 | — | — | EP | claimed |
| WO-2006123356-A1 | PROCESS FOR THE PREPARATION OF INDOLONE DERIVATIVE | ALEMBIC LIMITED (IN) | 2006-11-23 | — | — | WO | claimed |
| EP-1163250-B1 | IMPROVED SYNTHESIS OF ¬2.2.1|BICYCLO NUCLEOSIDES | EXIQON AS (DK) | 2006-07-12 | — | — | EP | claimed |
| EP-1501848-A1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | Santaris Pharma A/S (DK) | 2005-02-02 | — | — | EP | claimed |
| US-20040014959-A1 | Synthesis of locked nucleic acid derivatives | SANTARIS PHARMA A/S (DK) | 2004-01-22 | — | — | US | claimed |
| WO-2003095467-A1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | SANTARIS PHARMA A/S (DK) | 2003-11-20 | — | — | WO | claimed |
| US-4140684-A | FOR POLYESTERS, POLYAMIDES, AND CELLULOSE ACETATES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1979-02-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238876-A1 | PROCESS FOR THE PREPARATION OF ARIPIPRAZOLE | CYP2F1, CYP2C19, CYP2A6 | FAAH 1213/4885CA2 21/4885TSHR 2690/4885 |
| US-20100216983-A1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | RNGTT, NSUN3, NSUN2 | FAAH 2365/4885CA2 3961/4885TSHR 1240/4885 |
| US-20040014959-A1 | Synthesis of locked nucleic acid derivatives | NSUN3, RNGTT, NSUN2 | FAAH 2292/4885CA2 3938/4885TSHR 1165/4885 |
| US-20080262244-A1 | Process for the Preparation of Indolone Derivative | HTR3C, HTR3B, HTR1B | FAAH 2513/4885CA2 3810/4885TSHR 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.